Washington D.C., Jan.31 : Suffering from the woes of having frail bones? Unfortunately there are chances that your kid may inherit the 'brittle bone disease' from you, but thanks to science, you can protect your child by consuming less protein while you are pregnant.
Researchers at the University of Missouri School of Medicine have shown that limiting a specific maternal protein in pregnant mice with osteogenesis imperfecta resulted in offspring with stronger, denser bones.
Osteogenesis imperfecta, also known as brittle bone disease, is a genetic disorder that causes bones to break easily. Severe cases of the disease can result in hundreds of fractures during a person's lifetime or even death. The finding might one day provide a new therapeutic approach to treating brittle bone disease.
Ph.D., associate professor of biochemistry and child health at the MU School of Medicine, Charlotte Phillips, "Osteogenesis imperfecta is caused by the body's inability to make strong bones because of mutations affecting the production of the protein known as collagen".
She added, "No cure exists; however, we know from previous research that the prenatal environment can have a lasting effect on cardiovascular and metabolic health into adulthood. We studied whether bone health of mice could be improved by optimizing the environment within the womb."
She stated, "Myostatin is a protein that limits muscle growth. However, exercise causes myostatin levels to decrease - which is good because it allows muscle tissue to develop. Increased muscle tissue results in stronger bones".
Using mice with brittle bone disease, the MU researchers were able to identify the female as responsible for offspring bone health. The team also confirmed that female mice deficient in myostatin had offspring with stronger bones.
"Humans achieve 90 percent of their peak bone mass by age 19," Phillips said. "To approximate this timeframe with mice, we re-evaluated their bone strength and density four months after birth. In each case, the mice with stronger, denser adult bones were those whose fetal development involved females deficient in the protein myostatin.
This finding shows that the environment within the womb affects bone development not only at birth, but into adulthood."
The researchers believe that the work represents a paradigm shift in understanding and possibly treating osteogenesis imperfecta. The researchers also feel that their findings may prove beneficial to reducing the risk of other bone diseases such as osteoporosis later in life for many others. However, more research is needed. (ANI)Region: WashingtonGeneral: Health
Netflix CEO Reed Hastings presented his point against the executive order passed by President Trump to ban entry of people from seven Muslim-dominated countries. While Trump’s order has been challenged the court and has been stayed, CEOs of many technology companies have come forward to criticize the order. Talking about the immigration order, Hastings said, “Trump’s actions are hurting Netflix employees around the world, and are so un-American it pains us all.”
In his Facebook post, Hasting said, “Trump's actions are hurting Netflix employees around the world, and are so un-American it pains us all. Worse, these actions will make America less safe (through hatred and loss of allies) rather than more safe. A very sad week, and more to come with the lives of over 600,000 Dreamers here in a America under imminent threat. It is time to link arms together to protect American values of freedom and opportunity.”
Google CEO Sundar Pichai has also talked about the order passed by the U.S. President. Facebook, Microsoft and Uber also released statement condemning the order. The order has put a temporary ban on people coming from seven countries for 90 days to travel to the United States. The U.S. administration will figure out the best way to screen immigrants and President Trump said that there will be extreme vetting before people are allowed in the United States.
Thousands of protestors reached airports and many were also protesting on the street against executive orders passed by President Trump.Politics: General PoliticsRegion: United StatesBusiness: Technology SectorPeople: Donald Trump
Famed microbiologist Dr. Mark Wainberg, who played...Read More
Microsoft Corp. has claimed that it has already...Read More
Struggling to fight back soaring heroin and HIV...Read More
During the most recent Nintendo Direct, the mobile...Read More
Fresh Express is recalling a limited number of...Read More
Tech giant Google Inc. has plans to introduce a...Read More