Obese Monkeys Lose Weight, Shrink Waistlines with Novel Drug
Obese Monkeys Lose Weight, Shrink Waistlines with Novel Drug

As per latest reports, it has been revealed that the novel drug, dubbed Adipotide, is extremely effective in attacking white adipose tissue around the belly and underneath the skin.

During a recently concluded study, which was carried out by researchers from the University of Texas MD Anderson Cancer Center, the researchers were successful in developing a drug capable of attacking the blood supply of fat cells. During initial trial, the drug effectively inspired weight loss in obese rhesus monkeys.

At present, weight-loss medications are only effective in suppressing the hunger or escalating the metabolism of human body for winning over obesity, though experts have claimed that such apetitie suppressing drugs escort a handful of harmful side effects.

But now, the team of researchers, including Dr. Renata Pasqualini, of MD Anderson's David H. Koch Center for Applied Research for Genitourinary Cancers, and Wadih Arap, a professor at the Koch Center, has successfully designed a novel drug entitled “Adipotide”, with the intent of combating white adipose tissue.

As per experts, the said tissue is an extremely unhealthy form of fat that gathers around the belly and under the skin of an individual. Adipotide is made up of a homing agent that hangs on to a protein on the surface of fat-supporting blood vessels. As a result, cell death is caused by a synthetic peptide and due to a scarcity of blood supply, the body reabsorbs fat cells.

During the trial, researchers tested the drug on rhesus monkey models and in mice models.

The researchers claimed that Adipotide proved eventful in decreasing the Body Mass Index (BMI), abdominal circumference and unwanted fat. As per reports, the obese mice lost in excess of 30% of their total body weight due to Adipotide, while obsess rhesus monkeys responded with a 27% decline in abdominal fat levels.

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