Liver Cells Developed From Human Dental Pulp

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Liver Cells Developed From Human Dental Pulp

A group of Japanese researchers from the Nippon Dental University in Tokyo has conducted an experiment in which they have prepared liver cells from human dental pulp.

The research, which has been published in the Journal of Breath Research, has revealed that hydrogen sulphide (H2S), a major cause of bad breath, was the main component in transforming the cells into liver cells.

Lead author Ken Yaegaki said that they collected the pulp from the people who were coming in routine for dental checkups. He further affirmed that it is one of its kind research in which liver cells have been made from human dental pulp. The best part of the research is that the liver cells have been produced of great quality, which means there were fewer wrong cells.

“High purity means there are less 'wrong cells' that are being differentiated to other tissues, or remaining as stem cells. Moreover, these facts suggest that patients undergoing transplantation with the hepatic (liver) cells may have almost no possibility of developing teratomas (tumours) or cancers”, said Yaegaki.

It is a big win for the study researchers, but as per them, there is a long road ahead. Professor Anthony Hollander, who is head of cellular and molecular medicine at Bristol University, asserted that they need to ascertain that liver cell metabolizes specific toxins.

In order to test the fact they will need to conduct further research in which they will be required to conduct enzyme function tests. However, Yaegaki said that they have created something unique as otherwise fetal bovine serum is used to produce the cells.

If the research stands out with the time then there are chances that world will get treatment of numerable diseases such as Parkinson's and Alzheimer's.


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