Prostate cancer patients given hope by new 'triple-whammy' drug

.

Prostate cancer patients given hope by new 'triple-whammy' drug

At the annual meeting of the American Association for Cancer Research in Chicago, Harvard University scientists presented the results of a trial of a new drug - galeterone - which has recorded early success in treatment of advanced stage prostate cancer.

According to the scientists, the small phase one trial, involving 49 patients, showed that galeterone is effective in tackling advanced prostate cancer in three different ways --- it can block the "receptor" proteins which respond to testosterone; bring down the number of receptors in tumours; and successfully target an enzyme that is connected with hormone pathways involved in prostate cancer.

Revealing that the `triple whammy' galeterone drug has chiefly been developed for the treatment of cancer which stops responding to hormone therapy, the scientists said that even though the early galeterone trial results have been promising, the trial has been carried out on only a small number of patients.

The scientists also said that a larger phase two trial to further test the effectiveness of the drug, as well as to fully investigate the treatment's safety and all possible side-effects, has been planned for later this year.

Nonetheless, welcoming the results of the phase one trial - while also acknowledging that the new galeterone drug is in its "infancy" and full results are still to published -, Prostate Cancer Charity's research head Dr Kate Holmes said: "This very early stage research, conducted among a small group of men, indicates that galeterone shows potential as a new treatment for men with advanced prostate cancer."


Latest News

Californians Will Face Changes in Electricity Bill as PUC Gets Ready to Vote on
Increase in the Number of U.S. Oil Drilling Rigs Break the 29 Week Successive De
Though Employers Hire at Steady Rate Wages Remain Flat
Aetna Acquiring Medicare Insurer Humana for $37 Billion in Cash and Stock Combin
New Financial Worries Leave Greece Divided
Airlines Next on The Probe List of Justice Department’s Antitrust Division
Shutting Down the Wrong Engine Led to Crash of TransAsia Flight GE235 in Taiwan
Dominion’s Yorktown Oil Burning Unit to be Shut Down
Microsoft’s Monday Announcements; Agreement with AOL to Move Display Ads, Sells
Phil Knight, Nike’s Co-Founder will Leave the Chairman’s Post Next Year
In spite of Introducing Several Stimulus, China’s Economy Indicates Weakness
Puerto Rico’s Financial Problems Grow Further as Report Says It Can no Longer Me