Energy Balance of the Body Can Be Regulated By Heart

.

Energy Balance of the Body Can Be Regulated By Heart

A new research has proposed that the heart of a person can well regulate energy balance throughout body. It has been discovered that this study is the first of its kind to come up with the results which prove heart to be a regulator of the body.

A team of researchers from UT Southwestern Medical Center, carried out an experimental analysis on a genetically altered mouse, during which, they fed the mouse with a diet rich in fats. It was explained that the heart is assisted with two molecules, which are responsible for regulation. A drug which was capable to influence the working of these two molecules was even used in the analysis.

It was discovered that gene MED13, played an important role in gene pathway in the heart, which is responsible for managing the metabolism of body. These genes are responsible for protein coding. Another gene miRNA-208a, a heart-specific microRNA, was acknowledged, which inhibited the action of MED13.

It was analyzed that in case of mice, whose levels of MED13 were genetically altered and hence, increased or due to the manipulation of the drug, increase, were able to show up with an increase in energy levels.

However, in case of mice, whose levels of MED13 were decreased, had higher chances of getting obese due to the diet, they were given. Moreover, it was administered that the blood-sugar levels even fluctuated. Nevertheless, it was administered that the group of mice showed similar conditions as the ones encountered in case of people suffering from metabolic syndrome, including coronary artery disease, stroke, and type 2 diabetes.

Dr. Eric Olson, Senior Author of the study, said, “Several years ago, we worked with a biotechnology company to develop a drug to inhibit miR-208a. While studying the effects of that drug, we observed that animals treated with the inhibitor seemed to be resistant to high-fat diets”. The study has been able to put forth the role of miR-208a in regulating metabolism.


Latest News

To mark five years of operation to capture Osama, CIA tweets details
Sanders to continue fight for nomination
Reportedly, Englewood Based Sports Authority to Shutter All Stores in the U.S
Puerto Rico’s Governor says the American Territory Cannot Pay Most of its $370Mi
Chicago Mayor Says Hotel on Navy Pier Planned as Part of Navy Pier’s Centennial
Oil Field Service Provider Halliburton and Baker Hughes Give Up Plan of $28 Bill
Protestors demonstrate against Trump at California Republican Convention
Clinton more accepting of criticism
Abbott Laboratories Acquiring Medical Technology and Service Company St. Jude fo
Amazon Beats Expectations with Strong First Quarter Earnings Report
Michael Pearson, Valeant’s Outgoing CEO Admits Dramatic Increases of Certain Dru
Facebook Inc Posted a Better than Expected Revenue with Boost in Mobile Advertis