Recent research has indicated that excess of a protein could instigate development of Parkinson's disease, which is no less challenge for medical community. It has been claimed by researchers at the University of California, San Diego School of Medicine that alpha-synuclein protein could mar on alpha-synuclein protein, thereby escalating risk attached with the neurodegenerative movement disorder.
"I don't think anybody realised just how big a role alpha-synuclein played in managing the retrieval of worn-out proteins from synapses and the role of alterations in this process in development of PD", said principal investigator Mark H Ellisman.
It is to be noted that the disease fuels after some brain cells which have a tendency to produce dopamine are eventually destroyed. The research, which involved researchers from the University of Illinois, Urbana, noted that presence of considerably high amount of alpha-synuclein in the presynaptic terminal could result in hypertrophy. It leads to inhibiting the release of neurotransmitters, thereby raising chances for the neurons to stop functioning and dying gradually.
Published in The Journal of Neuroscience, the research has caught the attention of medical community as it raises hope that there would be some cure found in the near future for those who are suffering from the disease.
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