Enzyme Diabetes Makes One More Vulnerable to Heart Attack: Study

Enzyme Diabetes Makes One More Vulnerable to Heart Attack: Study

In the University of Iowa, researchers have said that the ones who are diabetic, they are more vulnerable to heart attacks.

A team of experts published their study in the Journal of Clinical Investigation. They deciphered that pacemaker cells had increased levels of oxidized CaMKII enzyme and more cell loss than pacemaker cells in a non-diabetic mice.

Experiment was performed on the mice with diabetes. They discovered that the patients who were suffering from diabetes, have higher levels of a heart enzyme called CaMKII (calcium/calmodulin-dependent protein kinase II). They found that the heart speed reduced for the mice carrying diabetes.

Similar to humans, mice with diabetes had double probability of having heart attack. They also said that for humans, diabetes type-2 increases a person's risk of dying from sudden heart attack.

Speaking on the findings, lead study author Min Luo, a cardiology fellow in the UI Department of Internal Medicine, said, "Our findings suggest that oxidized CaMKII may be a 'diabetic factor' that is responsible for the increased risk of death among patients with diabetes following a heart attack".

With the result of the finding, researchers have planned to hit the exact enzyme in the pacemaker cells may reduce the risk of sudden heart attack in people with diabetes type-2.

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