Scientists Scrutinize Gene Therapy for A Possible Cure Of Alzheimer’s

Scientists Scrutinize Gene Therapy for A Possible Cure Of Alzheimer’s

US Scientists have discovered a gene therapy to cure Alzheimer's Disease, characterized by loss of memory and creating difficulty in remembering recent incidents. Ageing is one the most common cause of Alzheimer's.

Scientists have found a way to keep the neurons communicating. Researchers at the Gladstone Institute of Neurological Disease in San Francisco believe that by increasing EphB2, a neurotransmitter can help in diminishing the worst effects of the condition. The researchers concluded that EphB2 could fix memory problems.

The scientist used gene therapy on a mice by artificially reducing and increasing the number EphB2 in the brain. When levels of EphB2 were reduced the mice developed the symptoms of Alzheimer's.

The researchers showed that amyloid interacts with EphB2. Therefore by increasing EphB2 or stopping amyloid from binding to it can help in treating the disease.

"We don't know yet if these findings will lead to a new treatment for Alzheimer's - that's some way off. It's critical we invest in research now to build understanding and investigate every potential treatment that could help people living with Alzheimer', said Rebecca Wood, Chief Executive of the Alzheimer's Research Trust, the UK's leading dementia research charity

 

General: