Enzyme PAM Linked to Small Cell Lung Cancer: Study

Enzyme PAM Linked to Small Cell Lung Cancer: Study

The hormone released after sex constitutes of an enzyme has been considered helpful, in treating the small-cell lung cancer.

Professor Chris Easton and PhD student Ms. Lucy Cao from the ARC Centre of Excellence for Free Radical Chemistry and Biotechnology at ANU were trying to develop new medicine with the understanding of the biology of small-cell lung cancer and the enzyme called PAM.

Their research has been published in the Royal Society Chemistry journal, Medicinal Chemistry Communications. This form of cancer is detected in 1 out of 28 Australians and the consequence of the disease is death, therefore finding treatment of this form of disease was necessary.

The enzyme PAM constitutes of calcitonin, which promotes cell proliferation and oxytocin, which develops the feeling of satisfaction following orgasm. Uneven count of peptide hormones in the body is claimed to result in occurrence of inflammatory diseases, asthma, and various cancers. It is the increase in calcitonin, which results in decreasing the life expectancy rates among small-cell lung cancer patients.

Therefore, the researchers have found ways in reducing the levels of calcitonin. As per Dr. Easton, "As we look to take these compounds into formal clinical trials we hope to provide a sexy new drug treatment to improve and extend the lives of many lung cancer sufferers".